Background
The Goldilocks mastectomy procedure involves local contouring of completely autologous breast tissue created by preserving and de‐epithelializing the residual mastectomy flaps. The purpose of this study was to provide outcomes data for 96‐Goldilocks mastectomy procedures analyzing indications, complications, relevant comorbidities, and adjuvant cancer treatment impacting reconstructive and aesthetic outcomes.
Methods
Comprehensive review of every patient who underwent Goldilocks mastectomy from 2012 to 2018 included relevant medical and surgical comorbidities, as well as complication profiles. Aesthetic outcomes were also assessed in those with postoperative imaging available.
Results
A total of 53 patients (96 breasts) were included in this study. Bilateral cases consisted of 81.1% of the total cohort (n = 86 cases), and 18.9% (n = 10 cases) were unilateral procedures. Mean age at the time of reconstruction was 55.8 (33‐77) years. Mean body mass index (BMI) at the time of reconstruction was 33.7 (19.2‐54.6). The overall complication rate was 9.38% (seroma = 2, hematoma = 1, cellulitis = 2, wound dehiscence = 3, and operating room take back = 1).
Conclusions
Goldilocks breast reconstruction is a safe, effective option in patients with higher than average BMI or excess local breast tissue, or in patients meeting these criteria preferring a single‐stage reconstruction. This study qualifies its use in patients with higher than average risk factors for more extensive reconstructive modalities.
Experiments were conducted on an AZ80 magnesium alloy by processing by high-pressure torsion (HPT) at room temperature (296 K) for up to 10 turns under an imposed pressure of 6.0 GPa. Measurements of the Vickers microhardness along diameters and through the disk thicknesses were recorded after HPT to evaluate the evolution towards homogeneity. The results show hardness increases up to a factor of approximately 2 and the deformation is more homogeneous along the disc diameter than through the thickness.
Background: Antimicrobial resistance is increasing at an alarming rate. The use of antibiotics without a prescription by a patient or other family members and their inappropriate storage have caused serious health issues as it would lead to antibiotic resistance and exposure to risk of harmful adverse effects unnecessarily. Exploring causes behind their storage in homes and reuse will help us identify the problem in depth and help in recommending effective solutions. Methods: This is a cross-sectional study. Our target study population was the residents of Saudi Arabia. Data were collected by an online questionnaire and analysed by SPSS. Results: A total of 738 participants answered the online questionnaire, from all ages, genders, nationalities, and different socioeconomic backgrounds residing in different regions across the kingdom of Saudi Arabia. 76.42% knew that an antibiotic is a chemical substance used to treat infections. The participants were questioned about when do they start using antibiotics, to which 95.66% (n=706) responded, after consulting a physician, 3.25% (n=24) said when they felt ill for any reason, and 1.08% (n=8) replied after first attempting herbal medicine. 147 participants admitted that they store excess pills of antibiotics after being prescribed for an infection and re-use them later on for symptoms like sore throat and fever. Conclusions: Although strict measures have been put into effect from the Saudi Ministry of Health to reduce antimicrobial resistance caused by misuse of antibiotics by restricting the dispense of antibiotics from pharmacies without a medical prescription, a large portion of the population regardless of age, level of education, or professional background, have continued to store excess pills of antibiotics after an infection treatment and re-use them once they think they need them for new symptoms. This advises for further revision of the current measures to fill those gaps and reduce this habit.
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