Anterior mediastinal masses arise from a diverse group of conditions including thymoma, teratoma, retrosternal goiter, thoracic aortic lesions and lymphoma. We report a case of a 70-year-old male with anterior mediastinal mass who on further evaluation was found to have a large mediastinal lymph node secondary to a papillary thyroid cancer. Metastatic lymph node mass from thyroid malignancy should also be considered as one of the differential diagnosis in the evaluation of anterior mediastinal mass.
Primitive neuroectodermal tumors (PNETs) and Ewing’s sarcoma (ES) belong to the same family of malignant, small, round cell neoplasms of soft tissue or bone origin. With just around 30 cases reported so far, primary pleuro-pulmonary PNETs/ES are extremely rare in adults. We herein describe a case of a hexagenerian male diagnosed with primary pleuro-pulmonary PNETs/ES after tissue biopsy. He underwent neoadjuvant chemotherapy, and after significant downstaging of the tumor, he underwent complete resection of the lesion through uniportal video-assisted thoracoscopic surgery (u-VATS) followed by adjuvant chemo-radiotherapy. He was disease-free while under close follow-up for the past 1 year.
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