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Particulate Metal Matrix Composites (PMMCs) have attracted interest for application in numerous fields. The current processing methods often produce agglomerated particles in the ductile matrix and as a result these composites exhibit extremely low ductility. The key idea to solve the current problem is to adopt a novel Rheo-process allowing the application of sufficient shear stress (τ) on particulate clusters embedded in liquid metal to overcome the average cohesive force or the tensile strength of the cluster. In this study, cast A356/SiC p composites were produced using a conventional stir casting technique and a novel Rheo-process.The microstructure and properties were evaluated. The adopted Rheo-process significantly improved the distribution of the reinforcement in the matrix. A good combination of improved Ultimate Tensile Strength (UTS) and tensile elongation (ε) is obtained.

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PurposeTranscatheter aortic valve implantation (TAVI) has been associated with large incidence of ischemic events, whose sources are still unclear. In fact, sub-acute complications cannot be directly related to the severity of the calcification in the host tissues, nor with catheter manipulation during the implant. A potential cause could be local flow perturbations introduced by the implantation approach, resulting in thrombo-embolic consequences. In particular, contrary to the surgical approach, TAVI preserves the presence of the native leaflets, which are expanded in the paravalvular space inside the Valsalva sinuses. The purpose of this study is to verify if this configuration can determine hemodynamic variations which may promote blood cell aggregation and thrombus formation.MethodsThe study was performed in vitro, on idealized models of the patient anatomy before and after TAVI, reproducing a range of physiological operating conditions on a pulse duplicator. The fluid dynamics in the Valsalva sinuses was analyzed and characterized using phase resolved Particle Image Velocimetry.ResultsComparison of the flow downstream the valve clearly indicated major alterations in the fluid mechanics after TAVI, characterized by unphysiological conditions associated with extended stagnation zones at the base of the sinuses.ConclusionThe prolonged stasis observed in the Valsalva sinuses for the configuration modelling the presence of transcatheter aortic valves provides a fluid dynamic environment favourable for red blood cell aggregation and thrombus formation, which may justify some of the recently reported thromboembolic and ischemic events. This suggests the adoption of anticoagulation therapies following TAVI, and some caution in the patients׳ selection.