Sixteen arene-Ru based molecular-rectangles were self-assembled in high yields by the equimolar mixing of arene-Ru acceptors (Aa-Ad) with various azopyridyl ligands (1,2-di(pyridyl-4yl)diazene (L1), 1,2-bis(pyridin-4-ylmethylene)hydrazine (L2), 1,2-bis(1-(pyridin-4-yl)ethylidene)hydrazine (L3), 1,2-bis(pyridin-4-ylmethylene)hydrazine (L4)) in nitromethane-methanol solutions. These new molecular-rectangles were fully characterized by a host of analytical techniques including elemental analysis, (1)H and (13)C NMR and HR-ESI-MS. The solid-state structures of two molecular-rectangles (1b and 4d) were determined by single crystal X-ray diffraction data. UV-visible and fluorescence studies were also carried out for the entire suite of rectangles. As with recent studies of similar arene-Ru complexes, the anti-proliferative activities of these complexes were evaluated against SK-hep-1 (liver cancer) and A-549 (lung cancer) human cancer lines. Additionally, the cellular pharmacology and intracellular localizations in AGS (gastric cancer) human cancer cells were determined for selected complexes (1c, 1d and 4c) by apoptosis and fluorescence microscopy studies. These studies confirm that arene-Ru molecular-rectangles inhibit cell cycle progression to the G0 phase, in contrast to that of cisplatin which arrests cell growth in the G2 phase.
The plasmonic coupling between the interacting noble metal nanoparticles plays an important role to influence the optical properties of arrays. In this work, we have extended the Mie theory results of our recent communication to include the effect of particle interactions between the alloy nanoparticles by varying interparticle distance and number of particles. The localized surface plasmon resonance (LSPR) peak position, full width at half maxima (FWHM) and scattering efficiency of one dimensional (1D) bimetallic alloy nanosphere (BANS) arrays of earlier optimized compositions i.e. Ag0.75Au0.25, Au0.25Cu0.75 and Ag0.50Cu0.50 have been studied presently by using discrete dipole approximation (DDA) simulations. Studies have been made to optimize size of the nanosphere, number of spheres in the arrays, material and the interparticle distance. It has been found that both the scattering efficiency and FWHM (bandwidth) can be controlled in the large region of the electromagnetic (EM) spectrum by varying the number of interacting particles and interparticle distance. In comparison to other alloy arrays, Ag0.50Cu0.50 BANS arrays (each of particle radius 50 nm) shows larger tunability of LSPR with wide bandwidth (essential condition for plasmonic solar cells).
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