Approximately 25 strains of lactobacilli isolated from different dairy products and fermented vegetables were screened according to their possibility to show the high auto-aggregation and co-aggregation. The strains Lactobacillus helveticus INRA-2010-H11, Lactobacillus rhamnosus INA-5.1, and Lactobacillus acidophilus JM-2012 were determined to have the high auto-aggregation (approximately 73, 46, and 70.5% correspondingly). A high co-aggregation capacity (75.53%) for strains INRA-2010-H11 and JM-2012 was shown. The adhesion degree of INRA-2010-H11 on the surface of buccal epithelial cells was 88.23%. The study of INRA-2010-H11, JM-2012, and both strains' mixture (1:1) adhesion capacity on the surface of epithelial HeLa cells revealed the adhesion of 1.1 × 10, 6.3 × 10, and 2.3 × 10 CFU, respectively, from starter amount of CFU 10 and 10 for both strains. In vivo experiments of LAB adhesion in gastrointestinal tract of mouse revealed the presence of 2.5 × 10, 1.2 × 10, and 1.5 × 10 CFU of LAB in control and groups of mouse, fed by INRA-2010-H11 and mixture, respectively. Feeding by investigated lactobacilli was suggested to lead to microbiota biodiversity reduction in small intestine and colon and its augmentation in stomach. Thus, INRA-2010-H11 demonstrated a high aggregation and adhesion activity so it has the potential as a good probiotic strain.
A mathematical model is constructed for land glaciers with the thickness much less than the horizontal dimensions and radii of curvature of large bottom irregularities by means of the method of a thin boundary layer in dimensionless orthogonal coordinates. The dynamics are described by a statically determinate system of equations, so the solution for stresses is found. For the general non-isothermal case the interrelated velocity and temperature distributions are calculated by means of the iteration of solutions for velocity and for temperature. Temperature distribution is determined by a parabolic equation with a small parameter at the senior derivative. I ts solution is reduced to the solution of a system of recurrent nonuniform differential equations of the first order by means of a series expansion of the small parameter. . A relatively thin conducting boundary layer adjoins the upper and lower surfaces of a glacier, playing the role of a temperature damper in the ablation area. For ice divides, the statically indeterminate problem is solved, so the result for stresses depends on the temperature distribution. RESUME. Modele mathematique d'un glacier a trois dimensions nonisotherme . Le modele mathematique est construit pour des glaciers terrestres d'epaisseur tres inferieure aux dimensions horizon tales et que les rayons de courbures des grandes irregularites du fond, par la methode de la fine couche limite en coordonnees orthogonales sans dimensions. La dynamique est decrite par un systeme d'equations determine statiquement, ainsi est resolu le probleme des contraintes. Pour le cas general non isotherme, le calcul des distributions interdependantes de la vitesse et de la temperature est realise par iteration des solutions pour la vitesse et la temperature. La distribution de la temperature est determinee par une equation parabolique avec un petit parametre pour la derivee seconde. La solution se ramene a la resolution d'un systeme d'equations differentielles non uniforme reccurentes du premier ordre par le biais d'un developpement en serie du petit parametre. Une couche limite conductrice relativemen t mince s'ajoute aux surfaces superieures et inferieures du glacier, jouant le role d'un egalisateur de temperature dans le zone d'ablation . Pour les cretes de glaces, un probleme statiquement indetermine est resolu , si bien que les resultats sur les contraintes dependent de la distribution de la temperature. ZUSAMMENFASSUNG. Mathematisches Modell eines dreidimensionalen nicht-isothermen Gletschers. Fur Land-Gletscher, deren Dicke bedeutend geringer ist als ihre horizontalen Abmasse und die Krummungsradien grosser Unregelmassigkeiten am Untergrund, wird mit Hilfe der Methode der dunnen Grenzschicht ein mathematisches Modell in dimensionslosen orthogonalen Koordinaten entworfen. Die Bewegungsvorgange werden durch das st<\tisch bestimmte Gleichungssystem erfasst, wobei sich die Losung fur den Spannungszustand ergibt. Fur den allgemeinen nicht-isothermen Fall werden die gegenseitig abhiingige Geschwindigkeit und ...
Acute experiments were performed on rabbits to study the responses of neurons in the anterior, ventromedial, and posterior nuclei of the hypothalamus to single, paired, and rhythmic stimulation of the vestibular nerve and lateral vestibular nucleus of Deiters. The data obtained showed that neurons of the posterior nucleus of the hypothalamus were the most sensitive. Three types of response were seen from hypothalamic neurons, with short, long, and intermediate latent periods. This provides evidence that ascending afferent spike activity from the lateral vestibular nucleus of Deiters to the hypothalamus is mediated by mono-, oligo-, and polysynaptic pathways.
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