Introduction: Gestational diabetes mellitus (GDM) is a common complication in pregnancy. Triglyceride (TG) to high-density-lipoprotein-cholesterol (HDL-c) ratio is an indicator of insulin resistance. Methods: Controversial findings of recent studies suggest that ethnicity and other possible factors may affect risk of developing GDM. In this study, 130 pregnant women of 18 to 35 years old were recruited. Demographic data as well as gestational age at the time of the test and blood glucose levels before and after oral glucose tolerance test were obtained from all subjects. TG/HDL-C ratios were significantly higher in women with GDM compared to controls. Results: The difference of mean levels of non-HDL-c and total-cholesterol was not statistically significant between cases and controls. The optimal cut off point for TG/HDL-C and GDM was 2.66
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