The problems of testing patients or the deceased using classical blood group systems for identity or paternity purposes after multiple transfusions are well known. In a paternity case where the putative father received multiple transfusions it was possible to determine some classical blood group systems. The investigation showed no incompatibility between the putative father and the child and led to a probability of paternity of 72.33%. Using the DNA technique (single locus probes) it could be demonstrated that the DNA patterns were not influenced by the transfusion and the possibility of paternity reached 99.9%. For a further consideration of this problem classical blood group systems and DNA systems were investigated in 12 patients before and after multiple transfusions. It was possible to determine the changes due to transfusion in the classical systems but changes in the DNA pattern were not observed.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.