The seed oils (petroleum ether extract) of three plants, Azadirachta indica, Annona squamosa and Pongamia pinnata were tested against the cyclops, Mesocyclops leuckarti sensu lato. Out of the seed oils tested, oil of Pongamia pinnata produced excellent cyclopicidal action followed by Annona squamosa. There was, however, no activity with Azadirachta indica oil. Further examination of chromatographic fractions of P. pinnata oil narrowed down activity to one of four fractions.
Introduction- Acinetobacter had gained increasing attention as a nosocomial pathogen causing severe, life-threatening hospital infections,
especially in intensive care units (ICUs). It is notorious to develop multi drug resistant. Management of multidrug-resistant Acinetobacter spp.
infections is a great challenge for physicians and clinical microbiologists. This study was designed to study the various species ofObjectives:
Acinetobacter prevalence and antibiotic susceptibility patterns of Acinetobacter sp. as isolated from patients lodged in intensive care units (ICUs)
of a tertiary care hospital in central India. The study was carried out in microbiology laboratory of a tertiary care hospitalMaterial & methods:
from July 2018 to July 2020. Samples were collected, processed and Acinetobacter isolates were identied by standard microbiological
procedures. Antimicrobial susceptibility testing performed by kirby-bauer disc diffusion method as per CLSI guidelines. Out of total 200Results:
isolates of Acinetobacter, ACB complex 189 (94.5%) was found to be the most common species isolated. Maximum isolates were obtained from
medicine intensive care unit. The most common infection was found to be pneumonia. Maximum isolates were resistant to Cetriaxone,
Ceftazidime, Ciprooxacin etc and least resistance was seen in Imepenem, Piperacillin-Tazobactum, Amikacin,. All the strains were sensitive to
Colistin. Acinetobacter has emerged as an important nosocomial pathogen showing high degree of resistance to most antimicrobials.Conclusion:
Early identication and continued surveillance of their antibiogram is essential for preventing the spread of Acinetobacter in hospital environment.
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