Following endoscopic hemostasis of bleeding ulcers, standard-dose PPIs infusion was as effective as a high-dose regimen in reducing the risk of recurrent bleeding. (ClinicalTrials.gov number, NCT00374101).

These findings support the hypothesis that properly performed digestive endoscopy is not a major risk factor for the transmission of HCV.

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Summary Background : Anti‐Helicobacter pylori therapy has been reported to cause regression of low‐grade gastric mucosa‐associated lymphoid tissue lymphoma in a high percentage of patients. However, in some patients, these lesions persist despite antibiotic treatment. Aim : To determine the various endosonographic findings that may predict the regression of low‐grade gastric mucosa‐associated lymphoid tissue lymphoma post‐antibiotics. Methods : Seventy‐six patients with Helicobacter pylori‐positive gastric mucosa‐associated lymphoid tissue lymphoma were studied. Follow‐up data were available on 51 patients. All patients were treated with antibiotics. Participants underwent pre‐ and post‐anti‐Helicobacter pylori therapy endoscopy with gastric biopsies, followed by endoscopic ultrasonography examination of the stomach. Results : Helicobacter pylori was eradicated in 45 of 51 (88%) patients. At the 2‐year follow‐up, complete regression of mucosa‐associated lymphoid tissue lymphoma was seen in 28 of 51 (55%) patients: 12 of 16 (75%) patients in stage T1m N0, 11 of 19 (58%) patients in stage T1sm N0, four of eight (50%) patients in stages T1m N1 and T1sm N1, and one of four (25%) patients in stage T2 N0. None of the stage T2 N1 patients achieved clinical regression. Conclusions : Endoscopic ultrasonography evaluation of gastric mucosa‐associated lymphoid tissue lymphoma plays a pivotal role in the initial staging and post‐treatment follow‐up evaluation of these lesions. Accurate staging is essential in the determination of the optimal treatment modality.