Background:
Hypertension is often associated with obesity. Uncontrolled hypertension can lead to uncorrected cardiac dysautonomia that makes cardiac repolarization abnormally prolonged. Modern dietary habits, stress and bad life style habits makes young adults vulnerable to hazards of health.
Purpose:
So we planned to study the association of BMI (Body Mass Index) and BP ( Blood pressure) with QTc (corrected QT interval) in young adults.
Materials and methods:
After obtaining the written informed consent, 171 subjects were randomly selected in the age group of 18-35 years. A general history and physical examination was done before recording the BMI and BP. A 12 lead ECG was recorded and QTc calculated using Bazett’s formula. The values obtained were compared and statistical analysis done.
Results:
Of the 171 subjects 14.03% were hypertensive. The QTc interval is found to be prolonged in females and it is prolonged with age, BMI and BP.
Conclusion:
QTc was significantly increased among the prehypertensive and hypertensive group and with overweight / obese BMI group compared to the normotensives and normal BMI group suggesting an altered autonomic homeostasis. This warrants lifestyle modification at a younger age to reduce the cardiovascular risk.
BACKGROUNDPCOS is a most common metabolic endocrine disorder affecting women of reproductive age group. Prevalence of obesity and overweight is observed more in patients with PCOS. The exact cause of PCOS remains unknown till now. Insulin resistance is considered to be a prime factor in the pathogenesis of PCOS. Insulin resistance may present in PCOS independent of obesity. Our study is aimed to investigate the role of adiposity with insulin resistance in patients with PCOS by evaluating the insulin resistance index in obese and non-obese PCOS patients.
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