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To analyze refractive results after hyperopic presbyopia surgery by Q-factor modulation without additive monovision.

Purpose To investigate structure function relationship between specifics parameters of structural damage analyzed by OCT RTVue100 (Optovue, Inc.) and CirrusHD‐OCT (Carl Zeiss Meditec) with functional parameters of standard automated perimetry (SAP). Methods 143 open angle glaucoma and 43 control eyes were included. They underwent a macular grid exam with RTVue100, CirrusHD‐OCT and 24°2 and 10°2 SAP (Humphrey SITA‐standard). Specifics structural parameters analyzed were Global and Focal Loss Volume (GLV and FLV) with RTVue, average and minimum Ganglion Cell and Inner Plexiform Layer (GCIPL) thickness with CirrusHD‐OCT. Functional parameters collected were MD, PSD and VFI for 24°2 SAP and MD and PSD for 10°2 SAP. A Student t‐test was performed to compare parameters and a logistic regression to calculate Pearson coefficient (r) studying correlation between structural and functional parameters. Results Glaucoma group had a significant functional (in 24°2 and 10°2 SAP) and structural impairment compared to control. Logistic regression analysis found a linear correlation between structural and functional parameters. The highest Pearson coefficient with OCT RTVue was between FLV and PSD in 24°2 SAP (r=0.72) and for CirrusHD‐OCT between minimum GCIPL and PSD in 24°2 SAP (r=0.56). Conclusion This study objectives a strucutre function relationship between specifics focal structural indices (FLV and GCIPL‐Min) assessed with these 2 SD‐OCT and functional (PSD) parameters damage. It would be interesting to confirm this new approch of SFR with these specific structural parameters.

Purpose To evaluate the glaucoma discriminating ability of macular inner layers measured by SD‐OCT (Cirrus HD‐OCT, Carl Zeiss Meditec (CZM) Dublin, CA, USA). Methods Our study concerns 252 primary open angle glaucoma (POAG) eyes (early, moderate and advanced glaucoma) and 337 normal eyes which underwent a visual field testing (Humphrey Field Analyser, SITA‐Standard 24‐2, CZM), and Cirrus HD‐OCT imaging (macular and optic disc cube 200x200). OCT macular scans were segmented into macular nerve fibre layer (mNFL), ganglion cell layer with inner plexiform layer (GCIPL) and ganglion cell complex (GCC=GCIPL+mNFL). Area under the receiver operator characteristic curve (AUC) for macular parameters and mean circumpapillary retinal nerve fibre layer (cpRNFL) were used. Results There is a statistically significant difference between glaucomatous and control eyes for all parameters (p <0.05). For early POAG group the best AUCs were respectively minimum GCIPL (0.747), average GCIPL (0.716), GCC (0.71), cpRNFL (0.704), minimum mNFL (0.673) and average mNFL (0.655). For moderate POAG group the best AUCs were respectively minimum GCIPL (0.864), GCC (0.858), cpRNFL (0.853), average GCIPL (0.838), average mNFL (0.82) and minimum mNFL (0.815). For advanced POAG group the best AUCs were respectively minimum GCIPL (0.938), GCC (0.928), minimum mNFL (0.92), average GCIPL (0.908), cpRNFL (0.854) and average mNFL (0.854). Conclusion Minimum GCIPL would have the highest sensitivity to diagnosis glaucoma. It may represent an interesting complementary parameter to cpRNFL thickness.