Background and aim: Dental plaque, a well-organized biofilm, is the established cause for gingivitis. Chronic gingivitis is the second most common disease of oral cavity which may progress to periodontitis. A mechanical plaque control method along with dentifrices is the most recommended method for plaque removal and controlling gingivitis. The aim of this review is to estimate and compare the effectiveness of herbal and non-herbal toothpastes in controlling plaque and gingivitis. Materials and methods: The primary focus of this study was to compare randomized control trials and clinical trials which used herbal toothpaste with non-herbal toothpaste in prevention of plaque and gingivitis. Clinical trials without randomization and other experimental studies were also included. The outcome measures were improvement in duration, objective and subjective difference in plaque accumulation, and gingivitis. Results: Randomized control trial and nonrandomized control trial has shown a remarkable reduction in plaque and gingival scores on an average duration of using herbal toothpaste. Studies (five randomized control trials and four clinical trials) state statistically equal reduction in plaque and gingival scores on using herbal and non-herbal toothpastes. No reports of adverse reactions (bad taste and odor, hard to accept, and allergic reactions) on using herbal toothpaste are evident. Conclusion: Nowadays, there is an increased interest on using herbal products among people. Herbal toothpastes are as effective as nonherbal toothpastes in controlling plaque and gingivitis. There are also no adverse reactions on using herbal toothpaste and can be used as an alternative to conventional (non-herbal) toothpaste. Henceforth, it depends upon the preference of people to choose natural (herbal) or conventional (non-herbal) toothpaste.
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