Introduction Krukenberg tumour (KT) refers to secondary malignant deposits in the ovary usually arising from gastrointestinal tract cancers. They are rare but pose a serious challenge in the management since the role of surgical debulking and chemotherapy and their effect on survival are controversial and still evolving. The aim of this study is to analyse the incidence, demographic profile, clinical features, management and survival of patients with KTs from gastrointestinal tract malignancy at our Institute. Methods This is a retrospective analysis of a prospectively maintained database at the Institute of surgical gastroenterology, Rajiv Gandhi Government General Hospital and Madras Medical College, Chennai, India between Jan 2015 to Dec 2017. Data of all patients with a diagnosis of KT from gastrointestinal tract malignancy were extracted. The
Touraine Solente Gole syndrome, a relatively rare inherited disorder is epitomized by finger clubbing, skeletal changes and pachyderma. We report a typical case of complete pachydermoperiostosis in addition to a thick fissured tongue, a yet unrecognized association and discuss the social cum clinical relevance of identifying this relatively uncommon disorder.
Primary hepatic lymphoma (PHL) is a lymphoma presenting with predominant liver involvement at presentation in the early stage of lymphoma. It accounts to less than 0.4% of all extranodal lymphomas and usually occurs in immunocompromised states. It is more commonly of the non-Hodgkin's lymphoma of B cell variety. Hodgkin's lymphoma presenting as PHL has not been reported before. We report a 55-year-old HIV positive male presenting with an SOL in left lateral segments of liver having typical imaging characteristics of fibrolamellar HCC with normal serum AFP levels. Surgical resection was done and the histopathological analysis and immunohistochemistry of the specimen revealed it to be a Hodgkin's lymphoma. The patient was started on chemotherapy (ABVD regimen) along with highly active antiretroviral therapy (HAART). Primary lymphoma of liver can mimic HCC on imaging. Hence, in the background of an immunocompromised state like HIV with normal serum AFP levels, PHL should be suspected and liver biopsy can clinch the diagnosis.
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