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Discrimination between signals produced by fat and by water is an important issue in MRI. One efficient approach is to perform fat-suppression by selective inversion. This technique exploits the transition region of a selective RF pulse to invert the longitudinal lipid magnetization while leaving the magnetization of the water protons untouched. The damaging effects of RF field inhomogeneity may be overcome by using pulses based on the adiabatic fast passage principle (AFP). In particular, the well-known sech/tanh adiabatic pulse is a robust and efficient pulse that is obtained as an analytic solution of the Bloch equation. In this paper, a wider class of analytic solutions of the Bloch equation is presented of which the sech/tanh driving function is merely a particular case. The new pulse exhibits an asymmetric distribution of magnetization with one transition sharper than the other. The sharper transition can be used to perform the required selective discrimination between signals. The resulting pulse features excellent adiabatic behavior. Moreover, the transition width of the new pulse can be reduced by a factor of about 2/3 with respect to an equal-duration sech/tanh pulse. The performance of the new pulse is compared with a similar sech/tanh pulse with the aid of a practical design example.

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