Purpose The purpose of this study was to develop an automated process to analyze multimedia content on Twitter during the COVID-19 outbreak and classify content for radiological significance using deep learning (DL). Materials and methods Using Twitter search features, all tweets containing keywords from both "radiology" and "COVID-19" were collected for the period January 01, 2020 up to April 24, 2020. The resulting dataset comprised of 8354 tweets. Images were classified as (i) images with text (ii) radiological content (e.g., CT scan snapshots, X-ray images), and (iii) non-medical content like personal images or memes. We trained our deep learning model using Convolutional Neural Networks (CNN) on training dataset of 1040 labeled images drawn from all three classes. We then trained another DL classifier for segmenting images into categories based on human anatomy. All software used is open-source and adapted for this research. The diagnostic performance of the algorithm was assessed by comparing results on a test set of 1885 images. Results Our analysis shows that in COVID-19 related tweets on radiology, nearly 32% had textual images, another 24% had radiological content, and 44% were not of radiological significance. Our results indicated a 92% accuracy in classifying images originally labeled as chest X-ray or chest CT and a nearly 99% accurate classification of images containing medically relevant text. With larger training dataset and algorithmic tweaks, the accuracy can be further improved. Conclusion Applying DL on rich textual images and other metadata in tweets we can process and classify content for radiological significance in real time.

We present a case of a 34-year-old male with coronavirus disease 2019 and uncontrolled blood sugar with right orbital cellulitis and right ethmoidal and maxillary sinusitis. Histopathology of a middle meatus tissue biopsy collected via diagnostic nasal endoscopy (DNE) revealed the presence of Mucor and Klebsiella pneumoniae (K. pneumoniae). After the administration of intravenous (IV) insulin, cefoperazonesulbactam, and posaconazole (due to the non-availability of amphotericin B), he underwent surgical debridement and functional endoscopic sinus surgery (FESS). After being on antibiotics and antifungals for two weeks post-surgery, the patient had a favorable outcome and further tests revealed improved blood counts and inflammatory markers.