A previous report of other researchers that aqueous phase fractions of erythrocyte stromata of secretors contained more ABH blood group activity than similar fractions of non-secretors was confirmed. The recovery of H activity in the butanol phase extracts of both secretors and non-secretors, which had not been seen previously, is reported here for the first time. Three H specificities were present when the aqueous and butanol phases of group O secretor stromata were examined in inhibition of agglutination studies with anti-H of group Oh and group A1 sera and three lectins. The anti-H (group Oh) sera were inhibited by both aqueous and butanol fractions. Anti-H serum (group A1) and the lectin Ulex europaeus were inhibited by the aqueous fraction only. The lectins Laburnum alpinum and Lotus tetragonolobus were not inhibited by either the aqueous or butanol phase extracts.
A new variant of blood group B characterized by a weak B antigen on the erythrocytes, anti-B present in the serum, and absence of B substance in saliva has been identified in four related individuals of Finnish descent. The condition appears to be inherited according to simple Mendelian principles. Weak B variants described by earlier investigators have been categorized into three groups on the basis of the serologic activity of their serum and the presence or absence of B substance in the saliva of secretors of H substance. This is believed to be the first report of a subgroup of B having anti-B in the serum but lacking B substance in saliva.
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