Colon-specific drug delivery have a great importance in the delivery of drugs for the treatment of local colonic, as well as systemic diseases like Crohn's disease, ulcerative colitis, colorectal cancer, amoebiasis, asthma, arthritis and inflammation which can be achieved by targeted delivery of drug to colon. Specific systemic absorption in the colon gave interesting possibilities for the delivery of protein and peptides. It contains relatively less proteolytic enzyme activities in the colon compared to the upper gastrointestinal tract (GIT). Recommended treatments included the administration of anti-inflammatory drugs, chemotherapeutic agents and antibiotics which must be released in the colon. Pectin is a naturally occurring polysaccharide has in recent years gained increasingly in importance in advance drug delivery. It was employed in pharmaceutical industry, health promotion and treatment. Owing to its gelling properties it has been used potentially as a carrier for drug delivery to the GIT, such as matrix tablets, gel beads, film-coated dose form. This review will discuss the important chemistry and general properties of pectin, its gel formation mechanism properties and its uses in novel drug delivery to the colon.

A series of new triorganotin compounds were synthesized and tested first time for their insecticidal and pesticidal activity against Periplanata americana, Musca domestica and Spodoptera litura and Tetranichus urticae of a pest crop mite and were found highly active against Spodoptera litura. It was found that these insects and pest highly damage the Indian crops and ultimately economy also.

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In this manuscript a series of new diorganotin (IV) dicarboxylates were screened out first time for their bio medicinal activity, like antimicrobial and in-vitro antitumor activity against different pathogenic bacterial and fungal strains along with human breast and mammary cancer cell line. It was found that the compounds show remarkable antitumor efficacy and moderate antimicrobial activity against pathogenic microbial strains.