In the remote sensing context spectral unmixing is a technique to decompose a mixed pixel into two fundamental representatives: endmembers and abundances. In this paper, a novel architecture is proposed to perform blind unmixing on hyperspectral images. The proposed architecture consists of convolutional layers followed by an autoencoder. The encoder transforms the feature space produced through convolutional layers to a latent space representation. Then, from these latent characteristics the decoder reconstructs the roll-out image of the monochrome image which is at the input of the architecture; and each single-band image is fed sequentially. Experimental results on real hyperspectral data concludes that the proposed algorithm outperforms existing unmixing methods at abundance estimation and generates competitive results for endmember extraction with RMSE and SAD as the metrics, respectively.
We describe a 29-year-old female who presented with rhabdomyolysis shortly after starting a course of sodium valproate. A thorough investigation revealed a likely mitochondrial origin inducing this susceptibility. An underlying mitochondrial disorder should be considered in all patients who present with undifferentiated disease whilst taking sodium valproate.
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