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Complex regional pain syndrome (CRPS) is a chronic neuropathic pain disorder characterized by hyperexcitability of the cen-tral nervous system and hypersensitivity to pain [1,2]. Sustained pain-related rumination, feeling of helplessness, and magnification of pain intensity are commonly observed symptoms of CRPS [1]. Considering the debilitating effects of CRPS on life quality, CRPS is a critical health problem, necessitating the development of strategies for prevention and intervention [3,4]. As the central hyper-sensitization underlies the mechanisms of CRPS [2], the pathophysiological mechanisms in the nervous system should be investigated in relation to .Previous studies have suggested that the chronic pain conditions may be closely related to the functional balance among somatosensory perception, sensory gating, and cognitive control [6][7][8].
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