In the present manuscript, the facile synthesis of tri-Schiff's bases, containing the core-thiophosphate moiety by using O,O,O-tris(4-formylphenyl) phosphorothioate, 3 and substituted anilines as a precursor has been reported. The key precursor 3 has been prepared under mild conditions in presence of (C4H9)4NBr as a phase transfer catalyst. All the synthesized compounds (5a-5h) were screened for their antibacterial and antifungal activities and were found to show good to excellent antibacterial and antifungal activities as compared to the standards.
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