The present study evaluated the effect of a one-day high-dose combined therapy on Helicobacter pylori infection. Thirty-two consecutive patients (suffering from either peptic ulcer or nonulcer dyspepsia) with Helicobacter pylori infection received omeprazole (40 mg) + bismuth subcitrate (240 mg x 4) + amoxicillin suspension (2000 mg x 4) + metronidazole (500 mg x 4), for only one day. Endoscopy, histology, culture, and susceptibility studies were done at entry and 30 and 90 days after the treatment day. Successful eradication was obtained in 23/32 (72%) patients and gastritis had resolved in 95% of these. Side effects were induced by the treatment in 6/32 (19%) patients, but these were all self-limiting, short-lasting, and did not require any specific treatment. Development of bacterial resistance to metronidazole occurred in 6/9 (67%) non-eradicated patients. These data suggest that one-day treatment with high doses of amoxicillin, metronidazole, bismuth, and omeprazole represents an effective, safe, and inexpensive therapeutic approach for the treatment of H. pylori infection.
Abstract:In ancient Rome, damnatio memoriae was a practice of erasing the memory of condemned persons from historical records after their death. This practice was usually addressed by the Senate to Roman elites and emperors who were declared enemies of the State, in order to preserve the honour of Rome. This condemnation usually included practices such as, for example, the erasure of names sculpted on inscriptions and the destruction or reworking of statues and of any other image of the person. Emperor Nero, for example, was condemned to this practice immediately after his death and a wide iconographic repertoire on him was therefore destroyed or deeply damaged. This lack of information can actually be improved thanks to the possibilities of virtual restoration and reconstruction offered by 3D digital technologies.The aim of this paper is to show how the possibility to acquire 3D reality-based data from archaeological finds allows experts to build 3D digital models that can be analysed and managed in a virtual environment and can be relocated, assembled or restored in order to suggest or graphically support archaeologists' interpretations and reconstructions. The paper shows the methodology developed for the virtual restoration of a statue of Nero starting from the 3D digitisation of the torso that was found 500 years ago near the Roman theatre of Bologna, Italy, the ancient Bononia.
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