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Objective. The aim of the study is to develop the design of a thermoelectric system (TPS) for thermal action on the anterior segment of the human eyeball, as well as to conduct its field studies.Method. The study is based on the methods of thermodynamic analysis, natural and computational modeling of processes and life support facilities.Result. The design of TPP for thermal impact on the anterior segment of the human eyeball is presented. Its fullscale studies were carried out in accordance with the existing methods of thermophysical measurements. Curves of changes in the temperature of the surface of the gelatin model of the human eyeball over time during cooling and heating were obtained for the supply currents of the thermoelectric module (TEM) included in the TPP, equal to 2.5 A, 3 A, 3.5 A, A and 1 A, 1 .2 A, 1.4 A, as well as changes in the temperature of the object of influence over time when changing the cooling mode to heating and vice versa. To assess the possibilities of heat removal from the hot junctions of TEMs in the system, data were obtained on the change in their temperature over time during the cooling effect for various values of the module supply current.Conclusion. It has been established that standard modules produced by domestic firms can be used as TEMs in the system. The duration of entering the TPP mode is about 230 s. The refore, it seems appropriate to bring the TPP to the operating mode before the actual procedures are carried out. It has been established that the duration of TPP switching from cooling to heating mode and vice versa is 230 s, which requires further optimization of the design and operating modes of the device through the use of more advanced types of TEMs and the use of forced operation of thermal modules in the transient mode.