Understanding the physical properties of the superconducting-to-normal transition is fundamental for optimizing the design and performance of transition-edge sensors (TESs). Recent critical current measurements of Mol Au bilayer test structures show that they act as weak superconducting links, exhibiting oscillatory, Fraunhofer-like
The proton T 1 was measured at 132 mT in ex vivo prostate tissue specimens from radical prostatectomies of 35 patients with prostate cancer. Each patient provided two specimens. The NMR and MRI measurements involved proton repolarization, a field of typically 150 mT and detection of the 5.6-kHz signal with a superconducting quantum interference device. Values of T 1 varied from 41 to 86 ms. Subsequently, the percentages of tissue types were determined histologically. The theoretical image contrast is quantified for each case by d 5 [1 -T 1 (more cancer)/T 1 (less cancer)]. A linear fit of d versus difference in percentage cancer yields T 1 (100% cancer)/T 1 (0% cancer) 5 0.70 6 0.05 with correlation coefficient R 2 5 0.30. Two-dimensional T 1 maps for four specimens demonstrate variation within a single specimen. These results suggest that MR images with T 1 contrast established at ultra-low fields may discriminate prostate cancer from normal prostate tissue in vivo without a contrast agent. Magn Reson Med 67:1138-1145,
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