FBP showed a protective effect for preservation during cold storage seeming to protect the mitochondrial membrane although it did not prevent reperfusion injury.
processes occurred. After 90 min recirculation, capillaries in f-rats continued t o remain open, whereas in g-rats almost 50 % of the capillaries were plugged by blood cells indicating poor perfusion of the fixative, evidently due t o the progressive capillary narrowing caused by endothelial destruction and increasing edema.Profuse lactic acidosis markedly aggravates the hypoxic-ischemic brain injury including capillary damage, which may secondarily lead to progressive impairment of circulation as edema develops in the damaged brain tissue.
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