Background: Papulosquamous lesions of the skin are encountered with considerable frequency. There is overlap of both clinical pattern and distribution of papulosquamous skin disorders, which often makes clinical diagnosis difficult. However, some of the histopathological features are specific and characteristic for each entity. Hence, combination of proper clinical observation and histopathological study will give a conclusive diagnosis. Material & Methods: A cross sectional study was done in department of pathology in which after satisfying inclusion criteria all papulosquamous lesion patients irrespective of age & gender were included in study in defined period. A brief history and dermatological examination was carried out. Skin biopsies taken were fixed in 10% formalin and subjected for tissue processing. The processed tissue was embedded in paraffin to obtain five-micron thin sections. The sections were stained with routine hematoxylin and eosin stain, followed by microscopic examination. Result: Out of 61 patients of papulosquamous lesion most common diagnosis was Lichen planus, (57.37 %) followed by Psoriasis (32.78 %). Commonest age group reporting Lichen planus & Psoriasis was 21-40 yrs. Male preponderance was noted in all papulosquamous lesion patients. Histological features commonly seen were hyperkeratosis, parakeratosis in both Lichen planus & Psoriasis patients.
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