Main"i JoeWAS~~~~~~~~~~~~~~~~~~~ secretion; and to the care necessary to avoid premature inhibition, by opiates, of its secretion and removal. Certainly we may wish to understand the underlying processes tlhat affect tle secretion of mucus, and if, as is perhaps the case, the primary.change, in a catarrh, is not so much one of bacterial infection as a change in the physiological equilibrium of the mucous membrane that allows scope to bacterial activities, it seems likely that, when we do attain such understanding, we may come to appreciate how it is that, during the epidemics we call "catarrlhal," there are associated cases and groups of cases, with affection of the cerebro-spinal system, not " catarrllal " in our modern sense, and yet a part of the " epidemic." To Fernel, Benedetto, Ballonius, and other physicians of the sixteenth century these nervous forms of disease were alternative to those we now call "catarrhal "-whether respiratory or gastro-intestinal-and the epidemiological unity of what we now call encephalitis, myelitis, and the like with what we now call in'fluenza was explained by them in terms of the famous doctrine of-' catarrh," wlhereby an "excretion" of the central nervous system, if "repulsed," set up nervous disease, but, if determined to a mucous membrane, produced bronchitis, diarrhoea, and so forth. To these physicians, then, a "defluxion" through the