A case of infantile acropustulosis is described. The condition responded to sulfones while it was not affected by any other therapy. Histologically, subcorneal pustules were found; persistent modest eosinophilia and eosinophils were present in the vesicular content, a feature never observed before. The significance of this finding is discussed.

A patient with hepatoerythropoietic porphyria had typical cutaneous manifestations: photosensitivity with blistering and mild scarring, and hypertrichosis. Biochemically elevated levels of protoporphyrins in erythrocytes, uroporphyrins in urine, and coproporphyrins in feces are markers of this form of porphyria. A family study confirmed that he was homozygous for a defect of uroporphyrinogen decarboxylase. A trial with hydroxychloroquine produced no improvement.