We conclude that urinary symptoms and pathological urodynamic findings increase along with the degree of motor function impairment shown by the GMFCS. Pathologic urodynamic findings can be found in both symptomatic and in asymptomatic patients.
Beta2-receptors play a main functional role in mediating relaxation of porcine detrusor. Selective beta2- and beta3-agonists similarly relax the human detrusor. Effects were smaller compared with the pig.
Parts of the study were selected as one of the 120 best poster presentations at the Annual Meeting of the AUA 2000, Atlanta Accepted for publication 2 June 2003 comprised men with bladder outlet obstruction in accordance with the AbramsGriffiths nomogram; group 2 (four men and four women, 56, SD 7.2 years) had detrusor instability; and group 3 (54, SD 9.6 years) had normal bladder emptying. BWT, as the detrusor force per cross-sectional area of bladder tissue (in N/cm 2 ), was calculated after a urodynamic evaluation and ultrasonographic estimate of bladder wall thickness.
RESULTSIn all patients it was possible to measure BWT; the mean ( SD ) maximum BWT in group 1 was 9.8 (3.9) N/cm 2 , in group 2 during bladder instability was 11.7 (2.6) N/cm 2 and in group 3 was 2.8 (0.5) N/cm 2 .
CONCLUSIONSEstimating BWT in humans is possible by combining a urodynamic evaluation with an ultrasonographic estimate of bladder wall thickness. Further clinical research should elucidate the clinical relevance of BWT under comparable conditions.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.