Microcirculation plays a decisive role in the metabolism processes between blood and tissue in both physiological and pathological conditions of the body. The analysis of changes in microcirculation provides a unique perspective for studying processes at the micro- and macrolevels in clinical and experimental medicine, including diseases in the maxillofacial region. Despite the critical role of microcirculation in many oral diseases, direct imaging and quantification of tissue microcirculation is currently limited. Scientific interest in microcirculatory monitoring is growing with the advent of new physical diagnostic methods. To date, there are many methods for assessing microcirculation. The purpose of this literature review is to show the positive and negative aspects of using various methods for monitoring microcirculation. The scientific literature was searched in the PubMed and Elibrary databases. As a result, the main shortcomings of various monitoring methods were emphasized, as well as what prospects for study and modification are possible today.
The purpose of the study: to trace the development of methods of bone implants for the replacement of jawbone defects: from ceramic and polymeric scaffolds to complex tissue-engineered structures with stem cells, growth factors and vascular anastomoses based on literature data.Materials and methods: searching, systematization and analysis of scientific data on various types of 3D-printed bone implants and their effectiveness in replacing bone defects.Conclusions: Modern technologies of 3D-printing, cell and tissue engineering, microvascular surgical techniques closely approach scientists and clinicians to creation of an artificial bone implant which in the body must become a living structure capable of integrating with the patient’s bone. Only complex approach which includes reconstruction of the implant of individual shape and sufficient mechanical strength, giving of osteoinductive and osteogenic properties, providing of internal axial and external angiogenesis is the basis for such tissue-engineered construction.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.