The article presents the results of a comprehensive study of patients to determine the type of xerostomia (true or false xerostomia) in somatic diseases — diabetes mellitus, peptic ulcer disease, hypertension. Xerostomia and hyposalivation were detected in varying degrees in these diseases in patients with complaints of dry mouth. In diabetes mellitus dry mouth was observed in all patients, in peptic ulcer disease and hypertension the number of patients with complaints of xerostomia was almost 2 times less. Decreased salivation rate, significant increase in surface tension and viscosity of mixed saliva in diabetic patients created conditions for the development of sialostasis, which manifested as complaints of periodic tumescent pain, periodic inflammatory salivary glands.
The goal. Studying the clinical course's features of acute odontogenic inflammatory processes of the jaws in children, describing species composition of pathogens, determination sensitivity to antibiotics of various groups in acute odontogenic infLammatory processes of the jaws in chiLdhood. Materials and methods. The case histories of 900 patients were analyzed, microbiological research methods were carried out (microscopic examination of clinical samples with Gram staining, culture method, determination of the sensitivity of the isolated pathogen to antimicrobial drugs). Results. The most common odontogenic inflammatory processes of the jaws were observed in children aged 4 -5 years. In 48,85 % of cases in a milk bite and in 67,92 % of cases in a permanent bite, the cause of the development of an odontogenic inflammatory process was complicated caries of the mandibular molars. 56% of children had a general condition. The leading causative agent of the inflammatory process of the jaws was in 65,6 % of cases hemolytic streptococcus. In other cases, Streptococcus Viridans (6,1 %), pneumococci (4,3 %), candida (3 %), Staphylococcus aureus (2,8 %), Moraxella cataralis (1,2 %), etc. were detected in the mixed microflora of purulent exudate. The drugs of choice for empirical antibiotic therapy for odontogenic inflammatory process caused by beta-hemolytic streptococcus group A are vancomycin (antibiotic sensitivity - 99 %), fluoroquinolones (antibiotic sensitivity - 98 %), beta-lactams (antibiotic sensitivity - 91 %). The highest percentage of resistance of this microflora was noted to macrolides (41 %), and to clindamycin (33 %). The rapid spread of the purulent-inflammatory process in the maxillofacial region in acute odontogenic processes in children, the resistant microflora of the odontogenic purulent focus require a competent approach when providing emergency care. Conclusions. The obtained has great practical importance for the choice of rational antibiotic therapy.
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