Background: Children who have hearing impaired need exceptional attention from their families, especially from mothers, as they are the most person contact with their children from birth and throughout life. Aim: The study aimed to assess the mothers' awareness towards care of their children suffering from hearing loss. Design: A descriptive design utilized in carrying out this study. Setting:The study conducted at the at hearing test unit at Hearing and Speech Institute outpatient clinics in Imbaba which affiliated to General Organization for Teaching Hospitals and Institutes, MOH, in Cairo. Sample: A convenient sample composed of 150 mothers having children suffering from hearing loss who attend to the previously mentioned setting. Tools: It consisted of three tools.(1) A pre-designed questionnaire sheet which consist of two parts: part(1) to assess characteristics of study subjects, part (2) to assess mothers' knowledge about hearing loss, (2) Mothers' reported practices regarding care of their children suffering from hearing loss and (3) Mothers attitude regarding care of their children suffering from hearing loss. Results: More than two thirds of the studied mothers have unsatisfactory knowledge about hearing loss and less than two thirds of them had inadequate reported practices regarding care of their children. In addition, less than three quarters of the studied mothers had positive attitude toward care of their children suffering from hearing loss. Conclusion: Based on the study findings, can be concluded that, there are strong positive correlations between mothers' total knowledge, total reported practices and total attitude regarding care of their children suffering from hearing loss. Recommendation: Conducting an educational programs for mothers to upgrade their knowledge, reported practices and communication with children suffering from hearing loss.