A simple interview on history of facial flushing after alcohol intake can be useful for identifying patients at high risk for synchronous or metachronous cancers of the UGI tract.

No abstract

Aim This study aimed to use a convolutional neural network (CNN) to investigate the associations between the time of falling and multiple complicating factors, including age, dementia severity, lower extremity strength and physical function, among nursing home residents with Alzheimer's disease. Methods A total of 42 people with Alzheimer's disease were enrolled. We evaluated falling events from nursing home admission (baseline) to 300 days later. We assessed the knee extension strength and Functional Independence Measure locomotion item and carried out the Mini‐Mental State Examination at baseline. To predict falling, participants were categorized into three classes: those who fell within the first 150 (or 300) days from baseline or those who did not experience a fall within the study period. For each class, 1000 bootstrap datasets were generated using 42 actual sample datasets, and were used to propose a CNN algorithm and cross‐validate the algorithm. Results Eight (19.0%), 11 (26.2%) and 31 participants (73.8%) fell within 150 or 300 days after the baseline assessment or did not fall until 300 days or later, respectively. The highest accuracy rate of the CNN classification was 0.647 in the factor combination extracted from the Mini‐Mental State Examination score, knee extension strength and Functional Independence Measure locomotion item score. Conclusions A CNN based on multiple complicating factors could predict the time of falling in nursing home residents with Alzheimer's disease. Geriatr Gerontol Int 2020; ••: ••–••.

Repetitive peripheral magnetic stimulation is a novel non-invasive technique for applying repetitive magnetic stimulation to the peripheral nerves and muscles. Contrarily, a person imagines that he/she is exercising during motor imagery. Resting-state electroencephalography can evaluate the ability of motor imagery; however, the effects of motor imagery and repetitive peripheral magnetic stimulation on resting-state electroencephalography are unknown. We examined the effects of motor imagery and repetitive peripheral magnetic stimulation on the vividness of motor imagery and resting-state electroencephalography. The participants were divided into a motor imagery group and motor imagery and repetitive peripheral magnetic stimulation group. They performed 60 motor imagery tasks involving wrist dorsiflexion movement. In the motor imagery and repetitive peripheral magnetic stimulation group, we applied repetitive peripheral magnetic stimulation to the extensor carpi radialis longus muscle during motor imagery. We measured the vividness of motor imagery and resting-state electroencephalography before and after the task. Both groups displayed a significant increase in the vividness of motor imagery. The motor imagery and repetitive peripheral magnetic stimulation group exhibited increased β activity in the anterior cingulate cortex by source localization for electroencephalography. Hence, combined motor imagery and repetitive peripheral magnetic stimulation changes the resting-state electroencephalography activity and may promote motor imagery.

A carefully targeted physical examination and performing a fine needle aspiration are essential to establish a diagnosis for the etiology of an unknown neck mass. In performing an open biopsy, the effect of an incisional biopsy on patients' survival was no worse than that of an excisional biopsy, despite the latter being theoretically preferable.