This work has provided a new, validated symptom score for patients with CKD not requiring RRT for clinical management and research purposes.
2019). Relationships between illness representations, physical activity and depression in chronic kidney disease. Journal of Renal Care XX(XX),1-9. S U M M A R YBackground: Chronic Kidney Disease (CKD) is exacerbated by depression and confers significant healthcare costs. Whilst adverse impacts may be mitigated by physical activity, many patients with CKD remain physically inactive, with this physical inactivity potentially influenced by how CKD is appraised. Objectives:The study aims to explore the relationship between physical activity, depression and illness representations in CKD. Methods: Patients with CKD but not requiring dialysis completed the Revised Illness Perception Questionnaire (IPQ-R), Beck Depression Inventory (BDI-II) and Short-Form International Physical Activity Questionnaire (IPAQ-SF). Demographic information was obtained via medical records. Correlation and regression analyses were conducted to determine the relationship of illness representations with levels of physical activity. Moderation and mediation analyses were performed to investigate the role of depression in any relationship between illness representations and physical activity levels.Results: Seventy respondents, 60 % male, with a mean age of 60 AE 16 years, took part in the study. Of illness representation dimensions, personal control was positively associated with levels of physical activity whilst timeline cyclical (a subscale of the IPQ-R relating to patient beliefs about the nature of their illness) was a significant predictor. Severity of depression was neither a moderator nor a mediator of illness representations and levels of physical activity. Conclusion:Facets of illness representations had significant relationships with levels of physical activity. Future research concerning the development and validation of psychological interventions based on an illness representations framework for patients with CKD not requiring dialysis is proposed. The efficacy of such interventions could be then evaluated using a randomised controlled method. K E Y W O R D S Chronic kidney disease Depression Illness perceptions Illness representations Physical activity B I O D A T A Alice Smith is Professor of Lifestyle Medicine at the University of Leicester and the University Hospitals of Leicester NHS Trust. Her primary research interest is the role of physical activity, exercise and lifestyle management in kidney disease. Her translational research programme encompasses laboratory-based exploratory and mechanistic work, and includes outcome measure evaluation, lifestyle intervention development and effectiveness testing, implementation and service evaluation. A strong track record of patient involvement and engagement, and qualitative exploration of patient perspectives and experience underpins all the work.
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