Amaranthus viridis L. belongs to family (Amaranthaceae). It is a common wild vegetable and weed of cultivation. Phytochemistry and antioxidant activity of Amaranthus viridis Linn. (Green leaf) were undertaken with standard methods. The phenolic and flavonoids compounds identified in leafy vegetable Amaranthus viridis demand a comprehensive pharmacological study. Amaranthus viridis contains several compounds like arginine, amino acids lysine, histidine, cystine, valine, phenylalanine, leucine, isoleucine, tyrosine, threonine, methionine, etc. In search of new activities pytochemical screening, chemical entities of the Amaranthus viridis extract from leaves, indicates the presence of biologically active constituents like tannins and phenols, saponins, alkaloids, flavonoids, cardiac glycoside, steroid and triterpenoids. Amaranthus viridis contains some chemical constituent that possesses potent anti-inflammatory, antiviral, antihepatotoxic, antiulcer antiallergic actions. Amaranthus viridis is used in Indian traditional system to reduce labour pain and act an anti-inflammatory and santipyretic. Other traditional uses range from an anti-inflammatory agent of the urinary tract, anti-rheumatic, antiulcer, venereal diseases vermifuge, diuretic, anti-rheumatic, antiulcer, analgesic, antiemetic, laxative, , antileprotic, improvement of appetite, treatment of eye problems and respiratory problems , to treatment of asthma. Also the phenolic and flavonoids compounds identified in leafy vegetable Amaranthus viridis demand a comprehensive pharmacological study

Amaranthus Viridis, is traditionally used for treatment of constipation, inflammation, eczema, bronchitis, anaemia, leprosy. Flavonoids are a group of polyphenolic compounds, which are widely distributed throughout the plant kingdom. Flavonoids like Rutin and Quercetin possess many biochemical effects like inhibition of enzymes, regulatory role on different hormones and pharmacological activities like antimicrobial, antioxidant, and anticancer, antihepatotoxic, protection of cardio vascular system. An HPLC method was developed for the estimation of rutin and quercetin from methanol herbal extract of Amaranthus viridis. Flavonoids like Rutin and quercetin possess many biochemical effects like inhibition of enzymes, regulatory role on different hormones and pharmacological activities like antimicrobial, antioxidant, and anticancer, antihepatotoxic, protection of cardio vascular system.