Braithwaite have all received grants from Genentech. C. Holweg is an employee of Genentech, a member of the Roche group. J. Matthews is employed by Genentech, a member of the Roche group, and is a named inventor on a pending patent application assigned to his employer relating to subject matter in the manuscript. R. Beasley reports grants from Genentech during the conduct of the study and personal fees from the Health Research Council of New Zealand, GlaxoSmithKline, AstraZeneca, and Novartis and grants from AstraZeneca, Chiesi, Cephalon, Genentech, Novartis, Sanofi Aventis, outside the submitted work. M. Weatherall declares that he has no conflicts of interest.
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