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In 1984, the Texas Legislature funded a four-university, interdisciplinary effort to identify feasible sites for location of a very high-energy physics lab in Texas and to evaluate the comparative advantages of one site versus another. Six feasible sites were identified and a comparative site analysis was made by applying Data Envelopment Analysis (DEA), incorporating project cost, user time delay, and environmental impact data. In addition, for the efficient sites, the price weights for user time delay and environmental impact, given normalization on project cost, were analyzed and arguments were developed to bracket these pairs of price weights into an “assurance region” for the preferred site(s). The South Dallas site was found to be preferred for a wide range of conditions, while the North Houston site was sensitive to the method of indexing the impact of the environment. The method appears to be applicable to a wide range of siting problems faced by not only government, but also industry.

BackgroundCurrently, little is known about physical activity patterns in pregnancy with prior estimates predominantly based on subjective assessment measures that are prone to error. Given the increasing obesity rates and the importance of physical activity in pregnancy, we evaluated the relationship and agreement between subjective and objective physical activity assessment tools to inform researchers and clinicians on optimal assessment of physical activity in pregnancy.Methods48 pregnant women between 26-28 weeks gestation were recruited. The Yamax pedometer and Actigraph accelerometer were worn for 5-7 days under free living conditions and thereafter the International Physical Activity Questionnaire (IPAQ) was completed. IPAQ and pedometer estimates of activity were compared to the more robust and accurate accelerometer data.ResultsOf 48 women recruited, 30 women completed the study (mean age: 33.6 ± 4.7 years; mean BMI: 31.2 ± 5.1 kg/m2) and 18 were excluded (failure to wear [n = 8] and incomplete data [n = 10]). The accelerometer and pedometer correlated significantly on estimation of daily steps (ρ = 0.69, p < 0.01) and had good absolute agreement with low systematic error (mean difference: 505 ± 1498 steps/day). Accelerometer and IPAQ estimates of total, light and moderate Metabolic Equivalent minutes/day (MET min-1 day-1) were not significantly correlated and there was poor absolute agreement. Relative to the accelerometer, the IPAQ under predicted daily total METs (105.76 ± 259.13 min-1 day-1) and light METs (255.55 ± 128.41 min-1 day-1) and over predicted moderate METs (-112.25 ± 166.41 min-1 day-1).ConclusionCompared with the accelerometer, the pedometer appears to provide a reliable estimate of physical activity in pregnancy, whereas the subjective IPAQ measure performed less accurately in this setting. Future research measuring activity in pregnancy should optimally encompass objective measures of physical activity.Trial RegistrationAustralian New Zealand Clinical Trial Registry Number: ACTRN12608000233325. Registered 7/5/2008.

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Overall there were no clear relations between dietary patterns and adult asthma; associations in nonsupplement users and whites require confirmation. The finding for chronic bronchitis was unexpected and also requires replication.

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This narrative review addresses scabies, a highly contagious, pruritic infestation of the skin caused by the mite S arcoptes scabiei var hominis . Scabies is a common disorder that has a prevalence worldwide estimated to be between 200 and 300 million cases per year. Infestation is of greatest concern in children, the elderly, immunocompromised people and resource-poor endemic populations at risk of chronic complications. A diagnosis of scabies involves a clinical suspicion, a detailed targeted history, clinical examination and contact tracing. Dermoscopy and microscopy, where available, is confirmatory. Due to its infectivity and transmissibility, the management for scabies requires a multimodal approach: topical antiscabetic agents are the first line for most cases of childhood classic scabies and their contacts, which must also be identified and treated to prevent treatment failure and reacquisition. Environmental strategies to control fomite-related reinfestation are also recommended. Oral ivermectin, where available, is reserved for use in high-risk cases in children or in mass drug administration programmes in endemic communities. The prevention of downstream complications of scabies includes surveillance, early identification and prompt treatment for secondary bacterial infections, often superficial but can be serious and invasive with associated chronic morbidity and mortality. Post-scabetic itch and psychosocial stigma are typical sequelae of the scabies mite infestation. The early identification of patients with scabies and treatment of their contacts reduces community transmission. Although time consuming and labour intensive for caregivers, the implementation of appropriate treatment strategies usually results in prompt cure for the child and their contacts. Here, we provide a summary of treatments and recommendations for the management of paediatric scabies.

This paper describes the findings of the research conducted by the authors on the humanitarian logistic efforts after the cascading disasters that impacted the Tohoku region after the Great East Japan Earthquake of March 11 th , 2011. Using a combination of in depth interviews with participants in the relief efforts and meta analyses of news accounts, the authors identified lessons learned by the participants, and the corresponding policy implications and suggestions for improvement of future response efforts.