The research work reported in this paper design a novel biodegradable multichamber microstructure for implantable drug controlled release by introducing the approach of topology optimization. It is therefore highly desirable to overcome these restrictions that pre-defined topology of the device result in difficulty to obtain a linear or pulsed drug release profile. The designed biodegradable multichamber microstructure is fabricated using UV-LIGA microfabrication and Micro-molding technique. The simulation results show that the multichamber microstructure exhibits a preferable linear drug release profile.
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