The ArrayExpress Archive of Functional Genomics Data (http://www.ebi.ac.uk/arrayexpress) is one of three international functional genomics public data repositories, alongside the Gene Expression Omnibus at NCBI and the DDBJ Omics Archive, supporting peer-reviewed publications. It accepts data generated by sequencing or array-based technologies and currently contains data from almost a million assays, from over 30 000 experiments. The proportion of sequencing-based submissions has grown significantly over the last 2 years and has reached, in 2012, 15% of all new data. All data are available from ArrayExpress in MAGE-TAB format, which allows robust linking to data analysis and visualization tools, including Bioconductor and GenomeSpace. Additionally, R objects, for microarray data, and binary alignment format files, for sequencing data, have been generated for a significant proportion of ArrayExpress data.

The BioSamples database at the EBI (http://www.ebi.ac.uk/biosamples) provides an integration point for BioSamples information between technology specific databases at the EBI, projects such as ENCODE and reference collections such as cell lines. The database delivers a unified query interface and API to query sample information across EBI’s databases and provides links back to assay databases. Sample groups are used to manage related samples, e.g. those from an experimental submission, or a single reference collection. Infrastructural improvements include a new user interface with ontological and key word queries, a new query API, a new data submission API, complete RDF data download and a supporting SPARQL endpoint, accessioning at the point of submission to the European Nucleotide Archive and European Genotype Phenotype Archives and improved query response times.

This paper presents information and results relevant for the development of a laser heat treatment process suitable to improve manufacturing in high strength steel and high strength aluminium alloys. The challenges with manufacturing of such materials include springback effect and localised fracture. The study details heat cycle and their effect in metallurgical state and mechanical properties. Such laser induced heat treatment process is intended to improve the forming behaviour of metal parts in challenging metal forming conditions, in particular for the delay or avoidance of localised fracture. Results for strength, hardness and elongation properties are presented. It was concluded that it is possible to locally modify yield strength and hardness using process duration suitable for industrial applications. Suitable process temperature ranges and target heat cycles were identified. A positive effect of material softening was observed in both hardness and strength properties. However, in some cases a reduction of ductility is apparent which must be considered for targeted industrial applications. The dimension of the heat-affected zone was also considered as design variable for the industrial process development. Preliminary results were obtained in a development forming tool.