GPAP results in clinically significant improvement in plaque and gingival index scores and histologically causes less gingival erosion than SBAP or ultrasonic instrumentation, further supporting the safety of this debridement technique in periodontal maintenance therapy.
A literature search was performed using MEDLINE (PubMed) and other electronic basis from 1991 to 2014. Search included books and journals based on the systematic and critical reviews, in vitro and in vivo clinical studies on molecular basis of host microbial interactions. Clearly, an understanding of the host susceptibility factor in addition to microbial factors by elucidating the molecular basis offers opportunity for therapeutic manipulation of advancing periodontal destruction. One of the hallmarks of pathogenesis is the ability of pathogenic organisms to invade surrounding tissues and to evade the host defence. This paper focuses the general overview of molecular mechanisms involved in the microbiota and host response to bacterial inimical behavior in periodontics.
A literature search was performed using MEDLINE (PubMed) and other electronic basis from 1991 to 2014. Search included books and journals based on the systematic and critical reviews, in vitro and in vivo clinical studies on Ozone therapy in dentistry. Ozone has been shown as powerful oxidizing agent capable of interacting as metabolic, immune modulator as well as an antimicrobial agent. It has been used to stimulate remineralisation of recent caries-affected teeth, as a preventive therapy in caries, root caries, intra-canal irrigants in endodontic treatment, treatment of alveolitis, avascular osteonecrosis of the jaw, herpes virus infection, to inhibits plaque formation, an adjuvant in periodontal surgical and maintenance phase and to disinfect implant surface and treat peri-implantitis and in water line to disinfect water.
Objectives:
Presence of
Helicobacter pylori
in the oral cavity may enhance the risk for gastric re-infection; hence, the present study was carried out to detect and compare the levels of
H. pylori
in subgingival plaque and saliva of patients with periodontal health and chronic periodontitis at baseline and 3 months following scaling and root planing (SRP).
Methods:
A total of 45 patients with 30 patients having chronic periodontitis (test group) and 15 periodontally healthy patients (control group) were considered.
H. pylori
was detected in subgingival plaque and saliva samples, collected at baseline and at 3 months using polymerase chain reaction. Clinical parameters were recorded at baseline, 1 month, 2 months, and 3 months.
Results:
At the baseline, in test group 60% and 40% of the samples were positive for
H. pylori
and in control group 26.7% and 13.3% of the samples were positive for
H. pylori
in subgingival plaque and saliva, respectively. At 3 months, 26.7% and 20% samples were positive for
H. pylori
in the test group and in control group 13.3% and 6.7% samples were positive for
H. pylori
in subgingival plaque and saliva, respectively, demonstrating higher levels of
H. pylori
in dental plaque than in saliva. There was a significant reduction in the percentage of
H. pylori
in subgingival plaque following SRP.
Conclusion:
Periodontal treatment has shown to be effective in reducing the levels of
H. pylori
from the oral cavity.
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