Two hemolytic peptides were isolated from the skin secretion of the Brazilian Hylidae frog Hyla biobeba, using reversed-phase chromatographic procedures. Hylins b1 and b2 exhibit short linear polypeptide chains, a large number of hydrophobic residues, amidated C termini and hemolytic properties. These two novel peptides are the first examples of bombinins H-like peptides isolated from anurans species not related to Bombina species.
We report a case of envenomation by
Dendrobates tinctorius
in
the northwest of the Amazon Forest. The patients were two men, who presented
with numbness in the right arm and slight numbness in the lower lip,
respectively.
Dendrobates tinctorius
secretions contain
pumiliotoxin, one of several toxins found in the dendrobatidis skin, which
interferes with muscle contraction and causes locomotor difficulties. Although
Dendrobatidae is a family of anurans known for their venom, few studies describe
the symptoms of envenomation in humans.
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