Abstract. We analyze the climate change signal in the Mediterranean Sea using the regionally coupled model REMO–OASIS–MPIOM (ROM; abbreviated from the regional atmosphere model, the OASIS3 coupler and the Max Planck Institute Ocean Model). The ROM oceanic component is global with regionally high horizontal resolution in the Mediterranean Sea so that the water exchanges with the adjacent North Atlantic and Black Sea are explicitly simulated. Simulations forced by ERA-Interim show an accurate representation of the present Mediterranean climate. Our analysis of the RCP8.5 (representative concentration pathway) scenario using the Max Planck Institute Earth System Model shows that the Mediterranean waters will be warmer and saltier throughout most of the basin by the end of this century. In the upper ocean layer, temperature is projected to have a mean increase of 2.7 ∘C, while the mean salinity will increase by 0.2 psu, presenting a decreasing trend in the western Mediterranean in contrast to the rest of the basin. The warming initially takes place at the surface and propagates gradually to deeper layers. Hydrographic changes have an impact on intermediate water characteristics, potentially affecting the Mediterranean thermohaline circulation in the future.

Vitamin D deficiency is associated with wide range of pathologies. Some evidences have shown that low vitamin D circulating levels in children and adolescent are related to fat mass and obesity. The objectives of the present study were to characterize vitamin D status in children and adolescents and to determine if serum 25-hydroxyvitamin D (25(OH)D) concentration is related to adiposity assessed by body mass index (BMI). Serum 25(OH)D levels were measured by LIAISON method in 471 children and adolescents (2 to 18 years age) and analyzed according to gender, pubertal period, age, and BMI. An overall prevalence of 25(OH)D insufficiency and deficiency was present in the 67.1%. Lower 25(OH)D levels were found in females (25.56 ± 14.03 vs 29.71 ± 17.10 ng ml; P = 0.004) and pubertal children (25.52 ± 13.97 vs 29.21 ± 16.83 ng ml; P = 0.011). In addition, an inverse relation of BMI and age on 25(OH)D concentrations was observed in children. In conclusion, low vitamin D status was highly prevalent among children and adolescents. Of note, a non-lineal regression model showed that 39.6% of vitamin D levels variability was explained by BMI. These results indicate that adiposity assessed by BMI impacts vitamin D status.

Abstract. We assess the role of ocean feedbacks in the simulation of the present climate and on the downscaled climate change signal in the Mediterranean Sea with the regionally coupled model REMO-OASIS-MPIOM (ROM). The ROM oceanic component is global with regionally high horizontal resolution in the Mediterranean Sea. In our setup the Atlantic and Black Sea circulations are simulated explicitly. Simulations forced by ERA-Interim show a good representation of the present Mediterranean climate. Our analysis of the RCP8.5 scenario driven by MPI-ESM shows that the Mediterranean waters will be warmer and saltier across most of the basin by the end of the century. In the upper ocean layer temperature is projected to have a mean increase of 2.73 °C, while the mean salinity increases by 0.17 psu, presenting a decreasing trend in the Western Mediterranean, opposite to the rest of the basin. The warming initially takes place at the surface and propagates gradually to the deeper layers.

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