Introduction: Tuberculosis (TB) is a ubiquitous, highly fatal contagious chronic granulomatous bacterial infection. It is mainly an infection of the lungs but can affect almost any part of the body. Although TB is a preventable and treatable disease, yet it still poses a significant threat globally. In 2012, an estimated 8.6 million people developed TB and 1.3 million died from the disease. Modern tuberculosis treatment relies on chemotherapy, surgery is accepted as adjuvant treatment for MDR TB. Methodology: This study include total of 40 diagnosed cases of MDR or XDR pulmonary tuberculosis with it's complications. Known cases of pulmonary tuberculosis with multidrug resistance and Extensive drug resistance with complications in Department of surgery, M.G.M medical college and M.Y Hospital, Indore. Result: The mean age of presentation was 38.82 ± SD years, Thoracotomy with Decortication was the most commonly performed procedure in (72.5% patients), Lobectomy in 20%patients, Pneumonectomy in 5% patients and Segmentectomy3% patients. Postoperative complication occurred in 10 patients (25%), 2 deaths occured in this study within 3rd postoperative day. Overall mortality was 5%, Out of 40 Patients complete cure was obtained in 85% of the treated patients, All patients had adjuvant chemotherapy post operatively for mean duration of 15.58 months with follow up for 12 to 18 months. Conclusion:The resectional surgery has a distinct role in the management of MDR/XDR tuberculosis. The proper selection of the patients and early decision for surgical intervention can achieve a high success rate of drug resistant pulmonary tuberculosis with well localised pulmonary lesion.
The present investigation entitled "Study of Path Coefficient Analysis of some Quantitative Traits in Wheat (Triticum aestivum L.)" was undertaken to study the path coefficient analysis for grain yield and its components. A set of twenty genotypes of Wheat were evaluated over two years from 2015-16 to 2016-17 to assess the genetic analysis of these genotypes for yield and its contributing traits over years and environments. Experiment was conducted in randomized complete block with 3 replications and two dates of sowing i.e. 3rd week of November (timely sown) and 1st week of January (very late sown). In the study number of tillers plant -1 showed highest positive direct effect on grain yield plant -1 , followed by biological yield plant -1 , harvest index, number of grains plant -1 , ear weight and number of spikelets ear -1 . It means direct selection of these traits may reward. However, days to maturity, plant height, days to 50% flowering, ear head length, peduncle length, 100 grain weight, number of ears plant -1 , number of grains ears -1 , number of dead tillers plant -1 and number of effective tillers plant -1 recorded negative direct effect on grain yield plant -1 . Greater part of indirect effects was recorded via other traits were only such traits viz., biological yield plant -1 , number of tillers plant -1 , number of effective tillers plant -1 /number of ears plant -1 , harvest Index, number of grains plant -1 , ear weight and number of spikelets ear -1 having high to moderate positive indirect effects. This indicated that these were main contributors to the grain yield.
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