Background: Contact lens has a growing popularity among people with vision impairment as well as for cosmetic reasons. However, its contamination can cause microbial keratitis. This study aimed to test the effectiveness of three antimicrobial contact lens solutions against microbial keratitis and to determine the contact time and adjustments in the existing label of multipurpose solutions. Aims and Objectives: To study the antimicrobial activity of three locally available contact lens solutions against Pseudomonas aeruginosa and Staphylococcus aureus and determined their contact time. Materials and Methods: Three bottles of each contact lens solution were evaluated using a single-blind controlled experiment method. These test solutions were categorized based on their identified disinfecting ingredient. This study evaluated the antibacterial activity of three contact lens solutions against P. aeruginosa and S. aureus at different contact times of 1, 3, 6, and 12 h. Results: All samples of contact lens solutions tested showed excellent antimicrobial activity. The contact lens solution B had the highest antibacterial activity against S. aureus and P. aeruginosa with a contact time of 6 h. Conclusion: The results showed that all the contact lens solutions demonstrate antimicrobial activity even after 24 h of exposure. Contact lens solutions containing polyhexamethylene biguanid as the active agent are found to have excellent antimicrobial activity and a desirable contact time.
Multipurpose contact lens solution / MPS (multipurpose solution) is a contact lens disinfecting solution to disable microbes that can cause infections in the eyes. The cause of the infection is the lessened activity of the multipurpose solution on the contact lens. The research aims to determine the antifungal activity of the multipurpose solution against Candida albicans and determine the time contact of the multipurpose solutions. This study evaluated the antifungal activity of five MPSs that were tested based on based on the International Organization for Standardization (ISO) 14729, with time contacts of 1,3,6 and 12 hours. The results showed that MPS has antimicrobial activity against Candida albicans with a contact time of 3 hours. MPS containing polyhexanide as the active agent was found to have excellent antifungal activity and a desirable contact time.
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