The global pandemic of COVID-19 has created havoc worldwide with its high transmission rate. The vaccine and drugs are still under trial; thus, the only option is to break the chain of transmission of disease by imparting the knowledge and designing awareness campaigns to educate people about the risks and preventive measures of COVID-19. This study was conducted to explore the knowledge and perception on health behaviors related to prevention along with addressing several myths and practices for COVID-19. An online cross-sectional survey was carried out in the initial days of disease outbreak in Nepal. A structured questionnaire was used for the data collection and recruitment of participants was done using snowball sampling technique. A total of 358 participants from all over the country were recruited for the study. Output measures were portrayed through descriptive statistical analysis with the use of frequencies (n) and percentages (%). Most of the participants (94.1%) knew about the high-risk age group, 38.5% were unaware that SARS-CoV-2 can be transmitted even from objects. Participants had better knowledge on modes of transmission of disease (77.1%) while 49.2% thought that regular surgical mask is highly effective for the preventive measure. Findings of this study suggests that people of Nepal are required to be educated about false beliefs and misconceptions. The findings and concerns raised in the study would be beneficial to design awareness-raising campaigns tailored specifically to the need for and understanding of the Nepalese community. Int. J. Soc. Sc. Manage. Vol. 7, Issue-4: 183-190
Introduction The role of NIV in SARS-CoV2 (COVID-19) related acute respiratory failure (C-ARF) is unclear. Methods C-ARF patients managed on NIV were categorised as NIV success or failure (death or intubation). Factors associated with failure were explored using regression analysis and expressed as Odds ratio (OR) with 95% Confidence Interval (CI). Results Between 1 st April 2020 and 15 th September 2020, 286 patients, age (Mean, SD) 53.1±11.6 years and APACHE-II score 11.1±5.5 were initiated on NIV. Of the 182 patients (63.6%) successfully managed on NIV alone, 118 had moderate or severe Acute Respiratory Distress Syndrome (ARDS). When compared with NIV success, NIV failure was associated with lower admission PaO 2 /FiO 2 ratio (p<0.001) and higher respiratory rate (p<0.001). On penalized logistic regression analysis, NIV failure was associated with higher APACHE (OR 1.12; 95%CI 1.01-1.24), severe ARDS (OR 3.99; 1.24-12.9), D-dimer ≥1000 ng/ml (OR 2.60; 1.16-5.87), need for inotropes or dialysis (OR 12.7; 4.3-37.7) and nosocomial infections (OR 13.6; 4.06-45.9). Overall mortality was 30.1%. In patients requiring intubation, time to intubation was longer in non-survivors than survivors (Median IQR 5 (3-8) vs. 3 (2-3) days, p<0.001). Conclusions NIV can be used successfully in C-ARF. Illness severity and need for non-respiratory organ support predict NIV failure.
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