This paper assessed challenges faced by lay women in promotion of socio-spiritual roles in St Charles Lwanga Hambale Catholic Parish in Vihiga County, Kenya. It discusses various roles various challenges lay women faces in their various socio-spiritual roles in the church. The study was conducted among various lay women in the five sub parishes within St Charles Lwanga Catholic Parish. This was based on the fact that lay women in the parish are the majority and the most active in their roles in the church hence a need to assess the challenges they face. Respondents were drawn from members of Small Christian Communities (SCCs), Leaders and some members from three lay women organizations which are: Catholic Women Association (CWA), Legion of Mary, and Sacred Heart. The study was based on both primary and secondary data collected and was descriptive in nature.