Epoxidation of alkenes is a significant reaction in organic chemistry due to its opportunities in producing compounds of biochemical interest. Catalytic epoxidation with first‐row transition elements has gained attention in the latest years wherein manganese based catalysts stand superior by satisfying numerous principles of green chemistry. In this review, we have summarized the recent developments in olefin epoxidation using homogeneous manganese catalysts. Manganese complexes with porphyrin, Schiff base, salen, and other non‐heme ligands made efficient catalytic systems during the last five years. Notably, we witnessed greener approaches in recent reports wherein photo‐catalysis is a promising strategy. We anticipate that the review will benefit the researchers to get a better understanding of the reaction and to choose the best catalysts for their reactions.

Nickel has emerged as a desirable substitute to Palladium in Sonogashira coupling reactions due to its abundance, less toxicity and high catalytic activity. Ni complexes have been developed to catalyse...

Owing to the advantages offered by fluorine in the pharmaceutical and agrochemical industry, the methods to incorporate fluorine have gained immense attention in the last two decades. Recently, several sustainable...

A new class of highly regio-and stereoselective intramolecular rearrangements of glycidol acetals to produce alkoxylated 1,3-dioxolane/1,3-dioxane is demonstrated. Selective Lewis acid activation of acetal generates an oxocarbenium ion that initiates the epoxide ring-opening event, giving the bicyclic [3,1,0]epoxonium ion intermediate that undergoes exo/endo-selective opening by a tethered alkoxide. Mechanistic insights into preferential acetal activation over the epoxide were obtained by crossover experiments. The method was applied in the total synthesis of parvistone B and its 8-ethoxy analogue.

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Heck coupling has emerged as an effective and powerful tool for CÀ C bond formations, with applications in academic and industrial grounds. The conventional Mizoroki-Heck reaction employed expensive Pd based catalysts, however, developments to meet low-cost replacements to Pd is relevant from a sustainable point of view. Heck-type couplings involving costeffective transition metals such as Fe, Co, Ni, and Cu have been established in the recent decades. Herein, we have comprehended the developments in low-cost transition metal-catalyzed Heck couplings covering the literature from 2016.

Amino alkylation of an acidic α-proton of a carbonyl by formaldehyde and a primary/secondary amine or ammonia, affording a β-amino-carbonyl compound also known as a Mannich base is a valuable reaction. We focus on recent advances in Zn catalysed Mannich reactions.