A Study on the prevalence of Plasmodium falciparum infection among pregnant women visiting community hospitals in Aguata LGA of Anambra State, Nigeria was carried out between October, 2014 and March 2015. Six hundred and five (605) pregnant women from 5 communities, who attended antenatal clinic during the research period, were involved in the study. Venous blood samples were collected and Plasmodium infection determined using microscopy of Giemsa stained thick and thin blood films. Of the 605 pregnant women sampled, 263 (43.5%) were infected. The prevalence by community was highest (67.4%) in Uga and least (29.9%) in Achina (P<0.05). Prevalence by age was highest (46.9%) in the age group (21-25) years and least (39.5%) in the age group (31-35) years (P>0.05). Highest prevalence (43.7%) was recorded among women that attained secondary school while women that attained tertiary education recorded the least (42.5%) prevalence (P>0.05). Farmers had the highest (81.8%) prevalence and the least (40.5%) was among traders (P<0.05). The highest prevalence (52.0%) was recorded among those in their second trimester and lowest (33.7%) among those in their third trimester (P<0.05). Women who started ANC in their third trimester had highest prevalence (56.5%) whereas those that started ANC in second trimester had least (37.6%) prevalence (P<0.05). With the high prevalence of Plasmodium infection in the study area, there is need for continual community enlightenment programs to reduce the burden of Plasmodium infection especially during pregnancy.
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