We present the case of a 28-year-old man who presented with chest pain and elevated cardiac biomarkers, with no evidence of acute ischaemia. He had a pronounced eosinophilia, abnormal echocardiographic, cardiac MRI and CT findings. He underwent transbronchial biopsy of carinal lymph nodes and of lung parenchyma. Endomyocardial biopsy yielded an eosinophilic infiltrate. He was treated with high dose glucocorticoids and made a rapid recovery. Testing for FIP1L1-PDGFRA and other BCR-ABL1 mutations was negative. Ultimately, he was diagnosed with eosinophilic granulomatosis with polyangiitis, also known as Churg-Strauss syndrome.
Original research article of hysterectomies performed annually (3-5), contributing to a large proportion of healthcare spend worldwide. The effects of endometriosis are wide ranging and include pain, infertility, inability to attend work and/or school, and depression, all of which have a negative impact on patients' quality of life (QOL). Despite its relatively high prevalence and large impact upon patients, the condition is underdiagnosed, with the average patient experiencing symptoms for 4-5 years before a diagnosis of endometriosis is made (6). The main factors to be considered when deciding as to whether hormonal medical treatment or surgical treatment of endometriosis is more appropriate are the success of medical treatment and the desire for pregnancy or need for contraception (7). Medical treatment of endometriosis is by means of analgesic therapy and hormonal therapy. Analgesic agents such as paracetamol, ibuprofen and mefenamic acid are commonly used first line for the treatment of dysmenorrhoea. This is despite the fact that little conclusive evidence exists regarding their efficacy, largely due to a paucity of good quality research data (8).
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