Adipokines are present in inflammatory processes and may be directly related to periodontal disease. Moreover, their activities may be regulated by fatty acids. The goal of this study was to quantify the concentrations of the main adipokines, leptin, adiponectin and resistin, and the docosahexaenoic (DHA), docosapentaenoic (DPA), eicosapentaenoic (EPA) and arachidonic (AA) fatty acids, in patients with generalized chronic periodontitis. As a secondary objective, the ratios of these substances in the blood of these patients were evaluated. The study included 15 systemically healthy patients with generalized chronic periodontitis (test group) and 15 patients with gingivitis (control group). Medical and periodontal parameters and blood samples were collected. Serum concentrations of fatty acids were analyzed by gas chromatography and adipokines by multiplex bead immunoassay. There was no significant difference in adipokines between groups. However, there was a tendency for lower values of adiponectin in periodontitis patients. Regarding the fatty acids, they were significantly higher in the test group compared with controls. The res/DHA, res/AA, adipon/DHA, adipon/AA and adipon/DPA ratios were significantly lower in the test group. There was no significant correlation between adipokines and clinical parameters and between adipokines and fatty acids levels. It was concluded that generalized chronic periodontitis patients showed significantly higher levels of fatty acids in comparison to gingivitis; adiponectin revealed a trend to lower values in the periodontitis group, even after Ancova correction. The ratios suggest a minor proportion of adiponectin and resistin in relation to the fatty acids in patients with generalized chronic periodontitis.
The aim was to identify the perception of Oral Health Planning (OHP) of basic care (BC) dental surgeons (DSs) in João Pessoa, Paraíba State, Brazil. Seventeen BC DSs from João Pessoa were interviewed. A qualitative analysis was performed using the Discourse of the Collective Subject (DCS) methodology. DCS obtained: Impact-"My work is effective when the user's need remains at the BC". Social Control-"The population participates in the organization of promotional activities, but I think it doesn't have enough maturity to opine on OHP". OHP Basis and Organization-"The OHP has a diverse organization and is based on user needs". It can be concluded that the knowledge of the DSs on OHP is varied. There is limited understanding about problem-solving. Social control is considered incipient and weak. It is understood that the organization of the local OHP assumes a diverse character and should be based on user demands.
Objetivo: propor a padronização do método e sua aplicação em pacientes com lúpus eritematoso sistêmico juvenil (LESJ). Material e métodos: soro de 50 pacientes, 25 com lúpus eritematoso sistêmico juvenil (grupo A) (idade média de 16,1 ± 1,6 anos) e 25 indivíduos saudáveis ??(idade média de 15,2 anos ± 2,3 anos) (grupo B) foi analisado. O método para detecção de anticorpos anti-PPAD foi cronologicamente realizado pela adição de: (1) peptídeo PPAD diluído (etapa de sensibilização), (2) albumina do soro bovino (BSA) (passo de bloqueio), (3) soro de cada paciente participante e (4) anticorpo monoclonal biotinilado diluído anti-IgG humana. Os passos finais consistia na adição de (1) proteína estreptavidina conjugada com peroxidase de rábano, (2) peróxido de hidrogênio e (3) uma substância cromogênica. Portanto, uma solução de parada foi adicionado para parar a reacção e a placa foi preparada para leitura espectrofotométrica a 450 nm. Resultados: os anticorpos séricos anti-PPAD foram detectados em ambos grupos. Conclusão: o método proposto é factível e efetivo para detecção desses anticorpos.
foram: população total, população cadastrada na Atenção Básica (AB), número e distribuição de aparelhos de Raios-X Odontológico (ARXO), e produção de radiografias odontológicas. As cidades que possuíam aparelho foram agrupadas e comparadas segundo as mesorregiões paraibanas. Calculou-se para cada cidade: a razão entre população total e quantitativo de aparelhos; a razão entre população cadastrada na AB e quantitativo de aparelhos públicos; produção semestral e média mensal de produção de radiografias. Das 223 cidades da Paraíba, 21,1% possuem ARXO, sendo 356 aparelhos em uso, 77,2% privados e 66,9% concentrados na Zona da Mata. A média de pessoas para cada ARXO do Estado é 16.609, enquanto a média de usuários cadastrados na AB para cada ARXO público é 20.922. A produção semestral e média mensal de radiografias ambulatoriais são, respectivamente, 1.272 e 212. Verificou-se que 36,2% das cidades não registraram produção de radiografias durante o último semestre de 2008. O serviço ofertado concentra-se em poucas cidades, sendo, majoritariamente, de caráter privado, com alta taxa de pessoas por aparelhos e distribuição desigual. Há, provavelmente, sub-registro da produção. Palavras-chave: sistemas de informação, radiografia dentária, Sistema Único de Saúde. Characterization of dental radiographic service in the state of Paraíba: highlighting inequalities and sub-records ABSTRACT. To characterize the dental radiology service in Paraíba State. From Department of Informatics of the Unified Health System, data collected were: total population, population covered by Primary Care (PC), number and distribution of dental X-ray equipment (DXRE), and dental radiographs production. The cities which had the equipment were grouped and compared according to Paraíba's regions. We calculated for each city: ratio between total population and amount of equipment; ratio between population covered by PC and quantity of public equipment; biannual and the monthly averages of radiographs production. Of the 223 cities, 21.1% are equipped with DXRE, which 356 are in use, 77.2% are private, and 66.9% concentrate in Zona da Mata region. The average of person per each DXRE is 16,609, while the average of people enrolled in PC for each public DXRE is 20,922. The biannual and the monthly production of radiographs are, respectively, 1,272 and 212. We found that 36.2% of the cities reported no X-rays production during the last half of 2008. The service is concentrated in a few cities, being mostly private, with a high rate of people per equipment and inequitable distribution. Probably, there is a production underreporting.
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