Parkinson disease (PD) is a neurodegenerative disorder affecting the central nervous system caused by the death of dopaminergic cells in the ventral region of the pars compacta of the substantia nigra. The subsequent lack of dopamine causes movement-related disorders including tremors, rigidity, hypokinesia, and postural instability. The clinical diagnosis of PD is hinged on the triad of asymmetric bradykinesia, rest tremors, and rigidity, with an expert (usually Prevalence and Predisposing Factors of Parkinson Disease used for statistical treatment. The research protocol was approved by the UST Faculty of Medicine and Surgery-Department of Clinical Epidemiology, as it adheres to the Declaration of Helsinki in clinical studies or surveys.
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